hrp0084fc14.5 | Puberty | ESPE2015

Polybrominated Diphenyl Ethers (PBDEs) and Timing of Puberty in Girls

Deodati Annalisa , Sallemi Alessia , Maranghi Francesca , Busani Luca , Cambiaso Paola , Mancini Francesca , Scire Giuseppe , Spadoni Gian Luigi , Marini Romana , Baldari Francesca , Tassinari Roberta , Cianfarani Stefano

Background: Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants and have shown endocrine disruption properties in experimental studies. Preliminary studies in animal models have suggested a link between exposure to PBDE and alterations of puberty and reproduction.Objective and hypotheses: To investigate the association between the exposure to PBDEs and alterations of puberty in girls, referred for idiopathic premature thelarche (IP...